CLinical Pharmacology Podcast β QSP Modeling in Drug Development
ποΈ Featured Podcast Appearance: Clinical Pharmacology with Nathan Teuscher Podcast
I recently joined Nathan Teuscher on the Clinical Pharmacology Podcast for a great conversation about
Quantitative Systems Pharmacology (QSP) and its growing importance in modern drug development.
We discussed:
- What QSP is and why it matters
- Where it brings the most value in model-informed drug development
- Common challenges teams face when adopting QSP
- Practical ways to overcome those challenges
It was a thoughtful and energizing discussion β big thanks to Nathan for having me on!
Listen to the Episode
π Episode Link:
QSP Modeling with Ahmed El-Mokadem β Ep. 51
Episode Overview
In this episode, we explore how QSP models can support better decision-making across the drug development lifecycle.
From early discovery through clinical translation, QSP provides a mechanistic framework for integrating biology, pharmacology, and clinical data β helping teams make more confident, model-informed decisions.
Whether youβre new to QSP or already working in the space, I hope the discussion offers useful insights into both the opportunities and the realities of implementing these approaches in practice.
Key Themes Discussed
- The definition and purpose of QSP
- How mechanistic models support MIDD strategies
- Communication and alignment challenges across teams
- Best practices for building impactful QSP programs
If youβre interested in QSP or improving decision-making with modeling, I hope you enjoy the episode.
Citation
@misc{elmokadem2025,
author = {{Ahmed Elmokadem}},
title = {CLinical {Pharmacology} {Podcast} β {QSP} {Modeling} in
{Drug} {Development}},
date = {2025-11-24},
url = {https://aelmokadem.github.io/aelmokadem/media/podcast-clin-pharm-1125/},
langid = {en-GB}
}